Abstract #5139

Evaluation of wave-CAIPI for accelerating MP2RAGE and FLAWS in deep-brain nucleus localization

Cuiliu Liu¹, Shuyue Wang¹, Yunzhu Wu², Wei-Ching Lo³, Daniel N. Splitthoff⁴, Peiyu Huang¹, and Jianzhong Sun¹

¹Department of Radiology, Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, China, ²MR Research Collaboration Team, Siemens Healthineers Ltd., Shanghai, China, ³Siemens Medical Solutions, Boston, MA, USA, Boston, MA, United States, ⁴Siemens Healthcare, Erlangen, Germany

Synopsis

Keywords:

Motivation: We tested the acceleration method in a clinical setting demanding high-resolution and high-quality structural images.

Goal(s): Deep -brain stimulation requires high-resolution 3D MRI sequences. The Wave CAIPIRINHA (Wave-CAIPI) may be expected to significantly reduce acquisition time while changing tissue contrast.

Approach: We collected scanning data from 5 healthy volunteers, including conventional MP2RAGE and Wave CAIPI research applications (with acceleration factors of 2x2, 2x3, and 3x3, respectively).

Results: Compared with MP2RAGE, the Wave-CAIPI (2Xx2) and Wave-CAIPI (2xX3) sequences provide good tissue contrast while shortening acquisition time.

Impact: This new sequence is helpful to the localization of brain structures for pre-surgical planning.

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