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Abstract #5182

Comparison of Magnetic Resonance Imaging–Based and Conventional Measurements for Proton Beam Therapy of Uveal Melanoma

Guido Rene van Haren1, Teresa Goncalves Ferreira2, Jan Willem Beenakker3, and Myriam Jaarsma-Coes1
1Radiology, LUMC Leiden, Leiden, Netherlands, 2Radiology, LUMC, Leiden, Netherlands, 3Radiology and ophtalmology, LUMC, Leiden, Netherlands

Synopsis

Keywords:

Motivation: Proton therapy is a relatively new option for treatment of uveal melanomas. For adequate treatment, accurate measurement of tumour dimensions and tumour-marker distance is essential. The dedicated MRI protocol for uveal melanoma patients developed in our institution could be helpful.

Goal(s): In this study, we compared MRI-based measurements with conventional ophthalmic measurements.

Approach: Retrospectively, MRI based measurements of tumour dimensions and marker-tumour distances in 23 patients were compared with conventional ophthalmic measurements and evaluated.

Results: MRI allowed for the three-dimensional assessment of the tumour. In specific patients, it provided a more reliable measurement of tumour dimensions and marker-tumour distances.

Impact: Dedicated ocular MRI proved to be a reliable tool for measurements required in the planning of proton therapy in patients with uveal melanoma.

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