Assessment of Bolus Injection Protocol with Appropriate Concentration for Quantitative Assessment of Pulmonary Perfusion by Dynamic Contrast-enhanced MR Imaging
Ohno Y, Murase K, Nogami M, Koyama H, Takenaka D, Hatabu H, Sugimura K
Kobe University Graduate School of Medicine
The purpose of the present study was to determine the appropriate concentration for quantitative assessment of dynamic contrast-enhanced pulmonary MR imaging. Pulmonary blood flow were calculated from dynamic MR data (PBFMR) with three different concentration protocols (protocol A: 0.1mmol/mL, B: 0.3mmol/mL and C: 0.5mmol/mL), and compared with perfusion SPECT (PBF Perfusion SPECT). PBFMR using protocol B in <70 kg group and protocol C in >/= 70 kg group showed no significant difference, when compared with PBF Perfusion SPECT. In conclusion, appropriate concentration of bolus injection protocol for 3D dynamic MR imaging provides accurate and reproducible assessments of regional pulmonary perfusion parameters.