Dynamic Tumor Regression during Radiation Therapy Predicts Treatment Outcome in Cervical Cancer
Wang J, Yuh W, Mayr N, Grecula J, Montebello J, Wu D, Wegner K, Gupta N, Edwards S, Knopp M
The Ohio State University
MRI-based volumetric tumor regression parameters (regression rate or area under regression curve) predicts long-term local tumor control and survival in cervical cancer. If tumor shows >10% residual volume at the conclusion of treatment, the risk for local failure and death are so high (> 80%) that aggressive intervention is warranted.