Combined stereoscopic X-ray and MR Imaging (XMR) for the evaluation of prostate brachytherapy implants with comparison to standard CT-based dosimetry.
Acher P, Miquel M, Rhode K, Keevil S, Mcleish K, Popert R, Beaney R, Morris S, Deehan C
King's College London, Guy's & St Thomas' NHS Foundation Trust
Introduction. Combined MRI and stereoscopic X-ray (XMR) may provide an alternative to CT for the dosimetric analysis of permanent prostate brachytherapy (PPB) implants. This study compares dosimetric results from both modalities.Methods. Ten patients underwent both a CT and an XMR study following PPB. Dosimetric analysis was carried out on both and parameters compared.Results. Bland-Altman analysis showed mean D90 values from XMR 1.1% higher than CT with wide limits of agreement (95% confidence interval) of -17.5% to 19.7%.Conclusion. XMR-based results are different to those from CT and are likely due to superior soft-tissue definition and source localisation.