Thomas Elgeti1, Michael Laule2, Nicola Kaufels1, Jrg Schnorr1, Uwe Hamhaber3, Dieter Klatt1, Sebastian Papazoglou1, Carsten Warmuth1, Bernd Hamm1, Braun Juergen3, Ingolf Sack1
1Department of Radiology, Charit - University Medicine Berlin, Berlin, Germany; 2Clinic of Cardiology, Charit - University Medicine Berlin, Berlin, Germany; 3Institute of Medical Informatics, Charit - University Medicine Berlin, Berlin, Germany
MR elastography (MRE) is capable to measure myocardial elasticity changes without intervention. The aim of this study was to investigate the correlation between LV-pressure and cardiac MRE-signal. Therefore, MRE was applied to three minipigs displaying individual variations of heart rate, systolic and diastolic pressure and pressure gradients. Tip manometers mounted on catheters were used to directly acquire LV-pressure functions over time. A good correlation of Cardiac MRE with invasively observed LV-pressure changes was observed. Individual variations of LV-pressure differences could be reproduced by MRE.