Jaeseok Park1, Eung Yeop Kim1,2
1Department of Radiology and Research Institute of Radiological Science, Yonsei University College of Medicine, Seoul, Korea; 2Brain Korea 21 Project for Medical Science, Yonsei University College of Medicine, Seoul, Korea
Small brain lesions such as multiple sclerosis (MS) are the most frequent inflammatory demyelinting disease of the central nervous system. T2-weighted imaging is a gold standard for diagnosing infratentorial brain lesions, while fluid-attenuated-inversion-recovery (FLAIR) imaging is known to be highly sensitive to lesions close to cerebro-spinal-fluid (CSF) but less sensitive in posterior fossa. Additionally, high-resolution three-dimensional (3D) imaging is preferred due to the small size of lesions. Given the facts above, the purpose of this work is to develop a novel phase-sensitive dual-acquisition single-slab 3D turbo/fast spin echo (SE) pulse sequence for acquiring both T2-weighted and CSF-suppressed images simultaneously in a single measurement.