Mies A. Korteweg1, Jaco J.M. Zwanenburg1, Vincent O. Boer1, Richard van Hillegersberg2, Paul J. van Diest3, Peter R. Luijten1, Willem P.Th.M. Mali1, Wouter B. Veldhuis1
1Radiology, University Medical Center Utrecht, Utrecht, Netherlands; 2Surgery, University Medical Center Utrecht, Utrecht, Netherlands; 3Pathology, University Medical Center Utrecht, Utrecht, Netherlands
We describe the pathology-correlated 7T MRI characterization of dissected sentinel lymph nodes of breast cancer patients. The mean absolute ADC and T1, T2, T2* relaxation times were determined. Nodal dimensions and the presence of a fatty hilus was scored. In 20 patients 83 nodes were excised and scanned, 17 contained metastases. Blood- and lymph vessels and an in-transit metastasis inside a lymph vessel were identified on MRI. While the location of intranodal metastases could not be delineated morphologically, there was a significant difference in T2 and T2* relaxation times between metastatic and non-metastatic nodes.