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Abstract #0529

Preliminary Human Evaluation of MRI-Guided Transurethral Ultrasound Therapy for the Treatment of Localized Prostate Cancer

Rajiv Chopra1,2, Michael Bronskill1,2, Masoom Haider3,4, Laurence Klotz5,6

1Imaging Research, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada; 2Medical Biophysics, University of Toronto, Toronto, Ontario, Canada; 3Medical Imaging, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada; 4Medical Imaging, University of Toronto, Toronto, Ontario, Canada; 5Urology, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada; 6Surgery, University of Toronto, Toronto, Ontario, Canada


MRI-guided transurethral ultrasound therapy is a minimally-invasive treatment for localized prostate cancer. The purpose of this study was to evaluate the feasibility of performing this treatment in humans. An initial clinical evaluation in prostate cancer patients destined for radical prostatectomy was performed. The predicted thermal damage zone was compared with the actual tissue damage measured on histology.