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Abstract #0530

Online Guidance of Tumor Targeted Prostate Brachytherapy Using Histologically Referenced MRI

Cynthia Menard1, Peter Chung, Jessamine Abed, Anna Simeonov, Jenny Lee, Kristy Brock, Warren Foltz, Gerald O'Leary2, Christine Elliott3, Michael Milosevic, Robert Bristow, Gerard Morton4, Padraig Warde, Masoom Haider

1Princess Margaret Hospital, University of Toronto, Toronto, Ontario, Canada; 2Toronto General Hospital, University Health Network, Toronto, Ontario, Canada; 3Sentinelle Medical Inc; 4Odette Cancer Center, University of Toronto, Toronto, Ontario, Canada


We demonstrate feasibility and report technical and clinical performance of a needle navigation system where pathologically referenced multi-parametric interventional MRI guidance improved the determination of tumor boundaries, and enabled accurate tumor-targeted HDR prostate brachytherapy. The value of 3D imaging to document actual location of biopsy cores in reference to anatomic boundaries is emphasized.