Abstract #1017

Double Spin-Echo Spiral Chemical Shift Imaging for Rapid Metabolic Imaging of Hyperpolarized [1-13C]-Pyruvate

Sonal Josan^1,2, Yi-Fen Yen³, Ralph Hurd³, Adolf Pfefferbaum⁴, Daniel Spielman², Dirk Mayer,¹²

¹SRI International, Menlo Park, CA, United States; ²Radiology, Stanford University, Stanford, CA, United States; ³Applied Sciences Laboratory, GE Healthcare, Menlo Park, CA, United States; ⁴Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA, United States

Undersampled spiral CSI (spCSI) with free induction decay (FID) acquisition allows real-time metabolic imaging of hyperpolarized ¹³C. Phase correction of the FID acquisition can be difficult, especially with contributions from aliased out-of-phase peaks. This work extends the spCSI sequence to incorporate a double spin-echo obtaining high quality spectra in magnitude mode. It also provides an added benefit of attenuating signal from flowing spins.