Su-Chin Chiu1,2, Chun-Juan Juan2,
Hsiao-Wen Chung1,2, Cheng-Chieh Cheng1,2, Hing-Chiu
Chang, 1,3, Hui-Chu Chiu4,5, Cheng-Hsien Hsu2,6,
Cheng-Yu Chen2, Guo-Shu Huang2
1Biomedical Electronics and
Bioinformatics, National Taiwan University, Taipei, Taiwan; 2Department
of Radiology, Tri-Service General Hospital, Taipei, Taiwan; 3Applied
Science Laboratory, GE Healthcare, Taipei, China; 4Department of
Nuclear Medicine, Tri-Service General Hospital, Taipei, Taiwan; 5EMBA
in Global Chinese Management, Tamkang University, Taiwan; 6Quanta
Computer Inc., Taipei
The
effects of fat saturation on quantitative perfusion measurements using
dynamic contrast-enhanced (DCE) MRI have not been documented for the parotid
glands. In this study we included phantom and in vivo studies to compare the
relationship between fat content and the difference between perfusion
parameters derived from non-fat-saturated (NFS) and fat-saturated (FS)
DCE-MRI. Significant differences were found for all amplitude-related
parameters in parotid glands but not for muscular tissue. It is suggested
that the use of FS or NFS should be explicitly specified for objective
comparison of perfusion parameters with DCE-MRI on fat-containing tissues
such as the parotid glands.