Peter Mannfolk1, Markus Nilsson1,
Ronnie Wirestam1, Freddy Sthlberg1,2, Peter Fransson3,
Andreas Weibull4, Johan Olsrud1,5
1Dept. of Medical Radiation Physics, Lund
University, Lund, Sweden; 2Dept. of Diagnostic Radiology, Lund
University Hospital, Lund, Sweden; 3Department of Clinical
Neuroscience, Stockholm Brain Institute, Karolinska Institute, Stockholm,
Sweden; 4Dept. of Medical Radiation Physics, Lund University,
Malm, Sweden; 5Center for Medical Imaging and Physiology, Lund
University Hospital, Lund, Sweden
Clinical
BOLD fMRI of children or in patients showing severe disease-related
impairment can be difficult as active participation is required. Therefore,
the possibility of using resting state data would be of great value. The aim
of this study was to evaluate the test-retest reliability in detecting the
intrinsic motor network from resting state data as compared to activation
maps based on a bilateral finger tapping task. The test-retest reliability of
resting state data was found to be comparable to what is seen for a typical
task based fMRI-experiment within a subject. However, large differences
between subjects were also found.