Alex M. Weber1, Peter Sheffield1, Michael D. Noseworthy2
1School of Biomedical Biomedical Engineering, McMaster University, Hamilton, Ontario, Canada; 2Electrical and Computer Engineering, School of Biomedical Engineering, McMaster University, Hamilton, Ontario, Canada
Herein we present the effects of ethanol on resting state blood oxygen level dependent fMRI signal using a novel fractal dimension (FD) analysis technique,correlated with proton MRS detection of ethanol. The FD structure of the resting state BOLD signal in normal healthy males decreased post ethanol ingestion. This correlated with significant ethanol concentration presence in the anterior cingulate cortex and basal ganglia. These findings, although only suggestive, shed further light on alcohols effect on the brain, specifically the brains functional connectivity.