Pan
Lin1, Simon Robinson1, Nicola De Pisapia1,
Jorge Jovicich1,2
1Center for Mind/Brain Sciences,
University of Trento, Trento, TN, Italy; 2Department of Cognitive
and Education Sciences, University of Trento, Italy
Characterization
of the default mode network (DMN) as a complex network of functionally
interacting dynamic systems has received great interest. However, it is still
unclear how DMN sub-regions interact during resting state and how these
interactions change when task performance. In this study, we used Granger
causality method to explore how intrinsic causal temporal interactions within
DMN sub regions during resting state may change when subjects perform a task.
We find that although the spatial scale of DMN maps during rest and task are
similar, the causal relationships in sub-regions show significant changes,
suggesting potential markers for potential clinical applications.