Ke Nie1, Daniel Chang1, Jeon-Hor Chen1,2, Tzh-Ching Shih1,2, Chieh-Chih Hsu2, Orhan Nalcioglu1, Min-Ying Lydia Su1
1Tu & Yuen Center for Functional Onco-Imaging, University of California, Irvine, Irvine, CA, United States; 2Department of Radiology, China Medical University, Taichung, Taiwan
There is a great interest to correlate between the density measured on MRI and mammogram, so the established role for mammographic density may be extended to MRI-based density. One problem specific to volumetric MRI analysis is the inclusion of skin as the dense tissue. In contrast this effect could be ignored on projection mammogram. In this study, we investigated the correlation between the volume of the skin and the breast on 3D MRI. We further provided two correction models aiming to provide an estimation of the skin volume and its effect on MRI based density measurement.