Sungheon Kim1, Anne Zeleniuch-Jacquotte2,
Malcolm C. Pike3, Silvia Formenti4, Linda Moy1
1Center for Biomedical Imaging, Radiology,
NYU School of Medicine, New York, NY, United States; 2Environmental
Medicine, NYU School of Medicine, New York, NY, United States; 3Preventive
Medicine, USC Keck School of Medicine, Los Angeles, CA, United States; 4Radiation
Oncology, NYU School of Medicine, New York, NY, United States
This
study was to investigate the feasibility of using MTR to differentiate breast
tissues with the patients undergoing diagnostic MRI scans at 3T. The MTR of
muscle (41.8 8.1 %) was significantly (p < 0.01) higher than that of
fibroglandular tissue (33.1 5.6 %). The MTR of fibroglandular tissue was
significantly (p < 0.01) higher than that of FCC (23.6 3.4 %). The
difference in MTR between FCC and tumor (20.1 4.2 %) was marginally
significant (p=0.04). In addition, MT images were able to accentuate the
signal differences in normal structures in the breasts.