R. G. Sah1,
U. Sharma1, R. Prashad2, N. R. Jagannathan1
1Departmet of NMR and MRI facility, All
India Institute of Medical Sciences, New Delhi, India; 2Departmet
of Surgical Disciplines, All India Institute of Medical Sciences, New Delhi,
India
This
study evaluates the potential role of magnetization transfer imaging (MTI) in
the differentiation of malignant and benign breast lesions at 1.5 T. The MT
ratio was determined in 72 women; 57 locally advanced breast cancer patients
(mean age, 43.8 9.0); 10 benign breast cases (mean age, 28.3 9.5) and 5
normal volunteers (mean age, 37.8 15.4). The mean MTR of malignant lesions
was statistically significantly higher (p=0.01) compared to the benign
lesions and the fibroglandular tissues of normal volunteers suggesting the
possible utility of MT imaging in the differentiation of various breast
tissues.