Jian Zhang1,2, Greg Zaharchuk2, Michael Moseley2, Eric Han3, Nate White4, Cooper Roddey4, Daniel Rettmann5, Anders Dale4, Joshua Kuperman4, Ajit Shankaranarayanan3
1Department of Electrical Engineering, Stanford University, Stanford, CA, United States; 2Department of Radiology, Stanford University, Stanford, CA, United States; 3Global Applied Science Lab, GE Healthcare, Menlo Park, CA, United States; 4Department of Neuroscience, University of California, San Diego, La Jolla, CA, United States; 5Global Applied Science Lab, GE Healthcare, Rochester, MN, United States
Pulsed Continuous Arterial Spin Labeling (PCASL) is a promising whole-brain perfusion imaging technique, with good properties such as high efficiency, 3D multi-slice capability, and low hardware demands. However, this sequence is vulnerable to patient motions due to its long scan time. We demonstrate an improved perfusion imaging strategy by integrating the original PCASL sequence with a PROspective MOtion (PROMO) correction module. The new sequence is much more robust against brain motion with little interference between the imaging volume and PROMO navigators.