Joshua M. Kuperman1,2, Timothy T. Brown,
23, Matthew J. Erhart, 23, J Cooper Roddey, 23,
Nathan Cooper White, 2,4, Ajit Shankaranarayanan5, Eric
T. Han5, Daniel Rettmann6, Anders M. Dale, 23
1Radiology, UCSD, La Jolla, CA, United
States; 2Multimodal Imaging Lab, UCSD, La Jolla, CA, United
States; 3Neurosciences, UCSD, La Jolla, CA, United States; 4Cognitive
Science, UCSD, La Jolla, CA, United States; 5Applied Science Lab,
GE Healthcare, Menlo Park, CA, United States; 6Applied Science
Lab, GE Healthcare, Rochester, MN, United States
In
order to test the utility of PROspective MOtion correction (PROMO) for
pediatric MRI research, nine children, ages 9-12, were scanned four times
with a high-resolution T1-weighted sequence.
For each subject, PROMO on and off scans were collected in a
counterbalanced alternating pattern.
Results show a qualitative enhancement in image clarity and reduction
of apparent motion artifacts with the use of PROMO. Furthermore, automated segmentations of
PROMO-enabled images show significant improvements in quality and reliability
as compared to PROMO-off images.
Volumetric segmentations of structures show consistently greater percent
volume overlap when PROMO is enabled.