Wei-Tang Chang1, Thomas Witzel2, Kevin Wen-Kai Tsai1, Wen-Jui Kuo3, Fa-Hsuan Lin1
1Institute of Biomedical Engineering, National Taiwan University, Taipei, Taiwan; 2Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, USA; 3Institute of Neuroscience, National Yang-Ming University, Taipei, Taiwan
To ensure a good BOLD contrast with TE = 34 ms at 3T, the scanning time of magnetic resonance inverse imaging (InI) can be further shortened to 25 ms per volume by using the echo shifting technique. Here we demonstrated the feasibility of using echo-shifted InI (esInI) with an unprecedented temporal resolution (40 Hz / volume) to detect hemodynamic responses of human visual cortex. Validated by EPI, esInI was found with good spatial localization using the minimum norm estimation (MNE) for volumetric reconstruction.