Pim van Ooij1,2, Annetje Gudon1,2, Joppe Schneiders1, Marcel C. M. Rutten3, Henk Marquering1,2, Charles B. Majoie1, Ed vanBavel2, Aart J. Nederveen1
1Radiology, Academic Medical Center, Amsterdam, Netherlands; 2Biomedical Engineering & Physics, Academic Medical Center, Amsterdam, Netherlands; 3Biomedical Engineering, Eindhoven University of Technology, Eindhoven, Netherlands
As a validation study for the use of phase contrast (PC) MRI in intracranial aneurysms high resolution time-resolved 3D PC-MRI was performed in a real-size patient-specific intracranial aneursysm phantom and compared with a CFD simulation. Qualitatively flow properties such as vortices and inflow jets were very similar. Quantitatively, small differences were found in root mean square error and velocity vector angles in voxels. This study is a first step in the application of PC-MRI in aneurysms in a clinical setting by showing that time-resolved 3D PC-MRI is capable of measuring complex flow patterns in small structures with an acceptable accuracy.