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Abstract #3152

MR Microimaging of Ex-Vivo Prostate Tissue at 16.4T

Gary Cowin1, Nyoman Dana Kurniawan1, Paul Sved2,3, Geoff Watson4, Roger Bourne5

1Centre for Advanced Imaging, the University of Queensland, Brisbane, Queensland, Australia; 2Department of Surgery, Faculty of Medicine, University of Sydney, Sydney, New South Wales, Australia; 3Department of Urology, Royal Prince Alfred Hospital, Sydney, New South Wales, Australia; 4Department of Anatomical Pathology, Royal Prince Alfred Hospital, Sydney, New South Wales, Australia; 5Discipline of Medical Radiation Sciences, Faculty of Health Sciences, University of Sydney, Sydney, New South Wales, Australia


Current clinical identification of prostrate cancer tissue using MRI is limited by the resolution and contrast, which has yet to approach the gold standard of histopathology of biopsy tissue. In this work, we present high-resolution diffusion and micro-MR imaging of prostrate biopsy samples in order to understand the underlying properties of the normal and cancer tissue contrast, and their correlation with low-resolution clinical MRI scans.