1Radiology/Psychiatry, UC San Diego, La Jolla, CA, United States
In clinical MRI, images are often acquired of the same anatomy with multiple forms of contrast. Mutual information has long been used as a criterion for aligning images with different contrast, as it is high for any pair of aligned images. We explore here the maximization of mutual information as a criterion in the joint reconstruction of pairs of under-sampled images with different contrasts. For T1 and T2 weighted images that were under-sampled by a factor of 1.9, maximizing mutual information resulted in excellent reconstructions in less than one second of reconstruction time.