1Laboratory for Structural NMR Imaging, Department of Radiology, University of Pennsylvania, Philadelphia, PA, United States
Relative to ultrashort echo-time (UTE), zero echo time (ZTE) imaging offers higher SNR and reduced image blurring for short-T2 imaging. However, ZTE imaging is time-consuming since it is inherently 3D and a complementary scan is needed to fill the missing central k-space portion. In this work, we designed a ZTE sequence with anisotropic filed-of-view (FOV) tailored to the elongated shape of the target anatomy to reduce the scan time. Point-spread function simulation verified the intended FOV shape. Both proton phantom imaging and ex-vivo cortical bone phosphorus imaging demonstrates the practicality of anisotropic FOV ZTE imaging.