Noriyuki Fujima1, Daisuke Yoshida1, Tomohiro Sakashita2, Akihiro Homma2, Yuriko Suzuki3, Hiroyuki Sugimori1, Khin Khin Tha4, Satoshi Terae1, Hiroki Shirato4
1Radiology, Hokkaido University Hospital, Sapporo, Hokkaido, Japan; 2Head and Neck Surgery, Hokkaido University Hospital, Sapporo, Hokkaido, Japan; 3Philips Electronics Japan, Minato-ku, Tokyo, Japan; 4Radiology, Hokkaido University, Graduate School of Medicine, Sapporo, Hokkaido, Japan
This study shows tumor blood flow (TBF) can be noninvasively measured using pseudo continuous arterial spin labeling in patients with head and neck squamous cell carcinoma. TBF can be useful information for estimation of prognosis and early detection of treatment effect. Moreover, TBF are considered as more sensitive indicator to determine treatment effect than conventional tumor volume measurement.