Regine Schmidt1, Dirk Graafen1, Stefan Weber1, Laura Maria Schreiber1
1Department of Radiology, Johannes Gutenberg University Medical Center, Mainz, Germany
The dispersion of a contrast agent bolus at myocardial perfusion MRI was simulated for a coronary bifurcation with stenosis in one branching vessel using the computational fluid dynamics (CFD) approach. Two sets of simulations for different outflow conditions through the stenotic branch were performed with four simulations for each set (rest and stress, pulsatile and constant velocity). We found a systematic underestimation of myocardial blood flow (MBF) up to -16.1% for pulsatile flow and an overestimation of the myocardial perfusion reserve (MPR) up to 7.5%.