Jack Harmer1, Nicolas Toussaint1, Kuberan Pushparajah1, Christian T. Stoeck2, Rachel W. Chan3, Reza Razavi1, David Atkinson3, Sebastian Kozerke, 12
1Division of Imaging Sciences and Biomedical Engineering, Kings College London, London, United Kingdom; 2Institute for Biomedical Engineering, University and ETH Zurich, Zurich, Switzerland; 3Centre for Medical Imaging, University College London, London, United Kingdom
Advances in diffusion acquisition schemes employing stimulated echoes now allow for robust DTI of the beating heart. When used in conjunction with respiratory navigation, data can be acquired during free breathing making it potentially feasible in patients. We demonstrate how in-vivo DTI data can be acquired in a patient with a systemic right ventricle, allowing novel insights into the adaptation of myofibre architecture in a morphological right ventricle supporting systemic circulation. This is to our knowledge the first record of in-vivo DTI of a systemic right ventricle. The technique has considerable potential for furthering our understanding of congenital heart disease.