Abstract #0208
High-resolution quantitative magnetization transfer imaging of post-mortem marmoset brain
Henrik Marschner 1 , Andr Pampel 1 , Roland Mller 1 , Nicholas A. Bock 2 , Marcel Weiss 1,3 , Stefan Geyer 1 , and Harald E. Mller 1
1
Max Planck Institute for Human Cognitive and
Brain Sciences, Leipzig, Saxony, Germany,
2
McMaster
University, Ontario, Canada,
3
University
of Amsterdam, North Holland, Netherlands
We present results of quantitative magnetization
transfer imaging (qMTI) in high resolution for
quantification of (qMT) parameters of otherwise MR-invisible
macromolecules. qMTI was performed on a post-mortem
marmoset brain at 3T and the results are compared to T1
mapping results obtained at 7T. The high resolution of
200 m permits visualization of cortical substructures
in the marmoset brain, as presented for the stria of
Gennari. An analysis of correlation between the
macromolecular pool-size fraction and T1 shows different
linear regressions in white and gray matter. This
suggests i) different myelination contribution in both
contrast parameters, or ii) other contributing factors.
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