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Abstract #0249

Combined MRI and TCD to assess association between different vulnerable plaque features in stroke patients

Martine Truijman 1,2 , Alexandra de Rotte 3 , Rune Aaslid 4 , Anouk van Dijk 5,6 , Madieke Liem 7 , Floris Schreuder 2,8 , Robert van Oostenbrugge 8 , Joachim Wildberger 1 , Paul Nederkoorn 7 , Jeroen Hendrikse 3 , Aad van der Lugt 5 , Werner Mess 2 , and Marianne Eline Kooi 1

1 Radiology, Maastricht University Medical Center, Maastricht, Netherlands, 2 Clinical Neurophysiology, Maastricht University Medical Center, Maastricht, Netherlands, 3 Radiology, University Medical Center, Utrecht, Netherlands, 4 Hemodynamics AG, Bern, Switzerland, 5 Radiology, Erasmus Medical Center, Rotterdam, Netherlands, 6 Neurology, Erasmus Medical Center, Rotterdam, Netherlands, 7 Neurology, Academic Medical Center, Amsterdam, Netherlands, 8 Neurology, Maastricht University Medical Center, Maastricht, Netherlands

Vulnerable carotid atherosclerotic plaque features, such as intraplaque haemorhage, fibrous cap status and microembolic signals, are frequently studied to identify those patients with an increased risk of a recurrent stroke. The purpose of this study was to investigate the relationship between these MRI and transcranial Doppler ultrasound determined features. The results show no significant difference in MES between patients with intraplaque haemorrhage or thin/ruptured fibrous cap. This indicates that MRI and transcranial Doppler ultrasound provide additive information on plaque vulnerability.

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