Multi-site, multi-vendor reproducibility of R2* relaxometry on an SPIO phantom at 1.5T and 3T
Diego Hernando 1 , Ihab Kamel 2 , Li Pan 3 , Ivan Pedrosa 4,5 , Shreyas Vasanawala 6 , Takeshi Yokoo 4,5 , Qing Yuan 4 , and Scott B. Reeder 1,7
Radiology, University of Wisconsin-Madison,
Madison, WI, United States,
Johns Hopkins University, MD, United States,
Technology, Siemens Corporation, Baltimore, MD, United
UT Southwestern Medical Center, Dallas, TX, United
Imaging Research Center, UT Southwestern Medical Center,
Dallas, TX, United States,
Stanford University, CA, United States,
University of Wisconsin-Madison, Madison, WI, United
Recently developed R2* relaxometry techniques may enable
rapid, accurate and robust liver iron quantification.
However, the reproducibility of these techniques across
multiple sites and MRI platforms has not been
established, precluding their widespread dissemination.
In this work, we studied the reproducibility of R2*
mapping on a phantom with different iron concentrations,
at four sites and on eight different scanning platforms
including 1.5T and 3T. Results demonstrate excellent
reproducibility across sites and platforms at each field
strength over a wide range of R2* values.
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