Design of Novel Synthetic Antiferromagnets for Nano-RF reporters for Single Cell Tracking
Karl F. Stupic 1 , Kathryn E. Keenan 1 , Edward V. Denison 1 , Charles A. E. Little 1 , and Stephen E. Russek 1
National Institute of Stanards and
Technology, Boulder, Colorado, United States
A new class of nanofabricated contrast agents, which
operate as nano-resonators, is proposed and modeled. The
agents are based on nanoscale synthetic antiferromagnets
(nano-SAFs) which have resonant modes that are
engineered to have large spectral densities at MRI
proton frequencies. The resonance frequencies can be
adjusted by tuning the layer thicknesses to give the
desired resonances at all clinical field strengths.
Initial nano-SAFs, with 830 nm diameter and 70 nm
thicknesses, have been fabricated and imaged at 1.5 T.
Strong T1 contrast was not observed indicating that
smaller dimensions are required.
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