Abstract #1725
Preliminary Investigation of Ultrashort T2* in Healthy Cervical Cord Grey Matter and White Matter In Vivo at 3T
Marios C. Yiannakas 1 , Bhavana S. Solanky 1 , Frank Riemer 1 , Daniel J. Tozer 1 , Hugh Kearney 1 , David H. Miller 1 , and Claudia A. M. Wheeler-Kingshott 1
1
Neuroinflammation, UCL - Institute of
Neurology, London, London, United Kingdom
In this work the feasibility of using ultrashort echo
time (UTE) imaging to obtain T2* measurements in grey
matter (GM) and white matter (WM) independently within
the upper cervical cord in vivo is investigated. A
linear fit of the natural logarithm in two echo times
(2-point fit) is used for the measurements. The results
show a distinct difference in T2* between GM and WM
which is suggestive of differences in macromolecular
structure. The method presented is clinically practical
and maybe used in the future to study neurological
disease affecting the spinal cord.
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