Differentiation of Malignant from Benign Focal Splenic Lesions: Added Value of Diffusion-Weighted MR Imaging
Jiyoung Hwang 1 , Kyung Mi Jang 2 , Seong Hyun Kim 2 , and Mi Hee Lee 3
Department of Radiology, Soonchunhyang
University Seoul Hospital, Seoul, Seoul, Korea,
of Radiology and Center for Imaging Science, Samsung
Medical Center, Sungkyunkwan University School of
Medicine, Seoul, Seoul, Korea,
Samsung Medical Center, Sungkyunkwan University, Seoul,
Purpose: To evaluate the added value of
diffusion-weighted (DW) MR imaging for differentiating
between malignant and benign focal splenic lesions.
Methods: This study included 53 patients with 11
malignant and 42 benign splenic lesions and who
underwent gadoxetic acid-enhanced and DW MR imaging.
Qualitative and quantitative analyses were conducted for
splenic lesions. Results: All malignant lesions showed a
hypovascular progressive enhancement pattern, while
hypervascular enhancement patterns were only
demonstrated in benign lesions (20, 47.6%) (P<0.05). The
mean ADC of malignant lesions was lower than that of
benign lesions (P< .001). The addition of DW images to
conventional MR images showed a significant improvement
for predicting malignant splenic lesions (P < 0.001)
Conclusion: The addition of DW imaging to conventional
MR imaging improves differentiation of malignant from
benign splenic lesions.
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