Abstract #2540
Hemodynamic Abnormalities Reflected by Low Diastolic Wall Shear Stress and High OSI as Potential Determinants of Lower Abdominal Aortic Atherosclerosis
Masataka Sugiyama 1 , Yasuo Takehara 1 , Yang Wang 1 , Shuhei Yamashita 1 , Naoki Ooishi 1 , Marcus Alley 2 , Tetsuya Wakayama 3 , Atsushi Nozaki 3 , Hiroyuki Kabasawa 3 , and Harumi Sakahara 1
1
Radiology, Hamamatsu University School of
Medicine, Hamamatsu, Shizuoka, Japan,
2
Radiology,
Stanford Unviersity School of Medicine, Palo Alto, CA,
United States,
3
Applied
Science Laboratory Asia Pacific, GE Healthcare Japan,
Hino, Tokyo, Japan
26 consecutive patients who were examined both with
4D-Flow and CT were enrolled in the study. 4D-Flow was
performed following 3D Gd-MRA. WSS and OSI of the aortic
wall were calculated. Based on the CT findings, 10
atherosclerosis and 16 non-atherosclerosis in the lower
abdominal aorta were subdivided. Multivariate logistic
analysis showed that Diastolic WSS (p = 0.0224) and OSI
(p = 0.0172) were independent determinant for the
presence of atherosclerosis. Hemodynamic abnormalities
reflected by low diastolic WSS and high OSI are
considered to be potential determinants of lower
abdominal atherosclerosis. 4D-Flow with an aid of flow
analysis software can provide these hemodynamic
parameters objectively.
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