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Abstract #2698

Whole-brain Perfusion Measurements at 7T using Pulsed Arterial Spin Labelling and Simultaneous Multi-slice Multi-echo Echo Planar Imaging

Dimo Ivanov 1,2 , Benedikt A Poser 1,2 , Laurentius Huber 3 , Josef Pfeuffer 4 , and Kmil Uluda─č 1,2

1 Department of Cognitive Neuroscience, Maastricht University, Maastricht, Netherlands, 2 Maastricht Brain Imaging Centre, Maastricht, Netherlands, 3 Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany, 4 Siemens Healthcare, Erlangen, Germany

Despite potential advantages of performing ASL at 7T, its successful implementation poses significant technical challenges related to SAR constraints and B1-inhomogeneities. In this work, we propose a combination of FAIR QUIPSSII labelling scheme, utilizing optimized tr-FOCI inversion pulses, and simultaneous multi-slice, multi-echo EPI readout for high-SNR whole-brain perfusion measurements. This approach offers high temporal resolution simultaneous CBF and BOLD measurements that can find application in both neuroscientific and clinical studies at 7T.

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