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Abstract #2897

Improved 3D MRSI on rat brain in situ with multicoil shimming

Sungtak Hong 1 , Christoph Juchem 1 , Peter B. Brown 1 , Kevin L. Behar 1,2 , and Robin A. de Graaf 1

1 MR Research Center (MRRC), Yale University School of Medicine, New Haven, Connecticut, United States, 2 Psychiatry, Yale University School of Medicine, New Haven, Connecticut, United States

In situ 3D magnetic resonance spectroscopic imaging (MRSI) was combined with focused-beam microwave irradiation (FBMI) and multicoil (MC) shimming. MC shimming has previously been shown to greatly improve the magnetic field homogeneity in vivo. Similar improvements were achieved on the FBMI samples as judged from B0 maps and water 3D MRSI datasets. As a demonstration of the improved data quality GABA-edited 3D MRSI was performed.

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