B1+ and B0 Corrected High Resolution Whole Brain T1-mapping at High Field in a Clinically Acceptable Scan Time
Govind Nair 1 , Qi Duan 1 , Daniel S Reich 1 , and Souheil Inati 2
NINDS, National Institutes of Health,
Bethesda, MD, United States,
National Institutes of Health, Bethesda, MD, United
B1-mapping techniques are seldom applied to T1-mapping
of the human brain at high field strengths due to the
high SAR resulting in long scan times.
Background-field-corrected Bloch-Siegert B1-mapping
scheme is used here for whole-brain T1-mapping at 1 mm
isotropic resolution on a 7T scanner. The total scan
time was less than 30 minutes. The corrected T1 map was
uniform and had a distinct bimodal distribution with
peaks at 1350 and 1950 ms, and repeat calculation at
non-optimal shimming yielded an average change of 0.1
0.1%. This technique is being applied in quantitative
lesion-evolution study in multiple sclerosis.
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