Accuracy of liver fat quantification by CT, MRI and US: a prospective comparison with Magnetic Resonance Spectroscopy (MRS)
Harald Kramer 1,2 , Mark A Kliewer 2 , Perry J Pickardt 2 , Diego Hernando 2 , Guang-Hong Chen 2 , and Scott B Reeder 2
Department of Clinical Radiology, University
of Munich, Munich, Bavaria, Germany,
of Radiology, University of Wisconsin - Madison,
Madison, Wisconsin, United States
Fatty infiltration of hepatocytes is the hallmark
feature of non-alcoholic fatty liver disease (NAFLD) and
potentially leads to inflammation, fibrosis and
cirrhosis. Since the currently accepted diagnostic
standard biopsy represents an invasive procedure and
samples only very circumscribed regions within the
liver, there is a need for a comprehensive, accurate and
non-invasive quantitative biomarker.
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