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Abstract #0255

Correlation analysis between renal perfusion and estimated glomerular filtration rate in volunteers and patients with chronic kidney disease: an arterial spin labeling in 3.0T MRI study

Yuelang Zhang 1 , Chenxia Li 1 , Jie Gao 1 , Xiang Li 1 , and Jian Yang 1

1 Department of Diagnostic Radiology, The First Hospital of Medical School, Xi'an Jiaotong University, Xian, Shaanxi, China

The aim of this study is investigate the correlation between renal perfusion and estimated glomerular filtration rate (eGFR) in volunteers and patients with chronic kidney disease (CKD) by using the flow-sensitive alternating inversion recovery technique in 3.0T magnetic resonance imaging (MRI). The results demonstrated that the significant difference in perfusion among healthy volunteers, CKD group with eGFR 60ml/min/1.73m2, and CKD group with eGFR< 60ml/min/1.73m2. Moreover, the perfusion values in CKD patients increased with the increase of eGFR. It indicates that FAIR-ASL can reflect the renal blood flow perfusion, thus indirectly reflecting early renal function change.

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