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Abstract #0256

Evaluation of Readout Schemes for Arterial Spin Labelling in the Human Kidney

Charlotte E Buchanan 1,2 , Eleanor F Cox 1 , and Susan T Francis 1

1 SPMIC, University of Nottingham, Nottingham, Nottinghamshire, United Kingdom, 2 Division of Medical Sciences and Graduate Entry Medicine, Royal Derby Hospital, Nottingham, United Kingdom

Readout schemes for multi-slice pulsed ASL of the human kidney at 3T are evaluated. Gradient echo (GE) based schemes of balanced fast field echo (bFFE) and gradient echo echo-planar imaging (GE-EPI) and spin echo (SE) based schemes of spin echo EPI (SE-EPI) and turbo spin echo (TSE) are compared for temporal SNR (tSNR), image SNR, spatial coverage, perfusion quantification and variability across slices and subjects. Gradient echo based schemes (bFFE and GE-EPI) provide optimal PWI-SNR and tSNR, with GE-EPI yielding multi-slice coverage in a short acquisition time.

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