Comparison of T2* correction methods for vertebral bone marrow fat quantification using chemical shift encoding-based water-fat imaging
Dimitrios C Karampinos 1 , Stefan Ruschke 1 , Michael Dieckmeyer 1 , Holger Eggers 2 , Hendrik Kooijman 3 , Ernst J Rummeny 1 , Jan S Bauer 4 , and Thomas Baum 1
Diagnostic and Interventional Radiology,
Technische Universitt Mnchen, Munich, Germany,
Research Laboratory, Hamburg, Germany,
Healthcare, Hamburg, Germany,
Technische Universitt Mnchen, Munich, Germany
Spine fat fraction mapping is emerging with growing
applications in osteoporosis and radiation therapy.
Vertebral bone marrow is characterized by short T2*
relaxation times. Therefore, vertebral bone marrow fat
quantification using chemical shift encoding-based
water-fat imaging needs to correct for T2* decay
effects. The present study compares different approaches
for T2* correction in water-fat imaging of vertebral
bone marrow using single-voxel MRS as a reference
standard. The advantage of a method correcting for a
common T2′ and using a priori known T2 relaxation times
for water and fat components is evaluated on the data
from 26 young healthy volunteers.
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