Abstract #0541
Arterial spin labeling in exercising calf muscle with prospective motion correction
Cline Giraudeau 1,2 , Benjamin R. Knowles 3 , Thomas Lange 3 , Michael Herbst 3,4 , Maxim Zaitsev 3 , and Pierre Carlier 1,2
1
NMR Laboratory, Institute of Myology, Paris,
France,
2
NMR
Laboratory, CEA, I2BM, MIRCen, Fontenay-aux-Roses,
France,
3
Department
of Radiology, University Medical Center Freiburg,
Freiburg, Germany,
4
John
A. Burns School of Medicine, Uni Hawaii, Honolulu,
Hawaii, United States
Acquiring clean ASL perfusion data in exercising
skeletal muscle is highly desirable and would have
significant impact for the pathophysiological mechanisms
of many conditions affecting the skeletal muscle,
primarily or secondarily. However, studies have been
limited to post-exercise data due to motion that
dramatically impairs perfusion curves. Recently,
real-time prospective motion correction (PMC) with
optical tracking has been proposed for brain and knee
MRI. In this work we investigated the potential of
PMC-augmented ASL to improve the quality of perfusion
curves acquired during calf muscle exercise.
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