Comparison of optimized endovaginal vs. external array coil T2-W and Diffusion-Weighted imaging techniques for detecting suspected early stage (Ia/Ib1) uterine cervical cancer
Kate Downey 1 , Veronica Morgan 1 , Alison MacDonald 1 , Sharon Giles 1 , John Shepherd 2 , Thomas Ind 2 , Ayoma Attygalle 3 , Steve Hazell 3 , and Nandita deSouza 1
CRUK Cancer Imaging Centre, The Institute of
Cancer Research and The Royal Marsden Hospital, Sutton,
Surrey, United Kingdom,
Surgery, The Royal Marsden Hospital, London, United
The Royal Marsden Hospital, London, United Kingdom
Endovaginal MRI using T2-W sequences is more sensitive
(87% vs. 73.9%) but less specific (80% vs. 93.3%) than
equivalent optimized external array imaging for
detecting suspected Ia1/2 and Ib1 cervical tumors.
Addition of diffusion-weighted sequences to T2-W
protocols obtained with an endovaginal coil
substantially improves specificity (80% to 93.3%).
Addition of diffusion-weighted imaging to T2-W protocols
acquired using an external array coil however merely
serves to reduce sensitivity (73.9% to 65.2%) for
detecting these small (1cm) tumors.
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