Abstract #0641
Assessment of Fetal Fat Distribution with Water-Fat MRI
Craig Olmstead 1 , Lanette Friesen-Waldner 2 , Abraam Soliman 3,4 , Kevin Sinclair 2 , Barbra de Vrijer 5 , and Charles McKenzie 2,3
1
Schulich School of Medicine and Dentistry,
University of Western Ontario, London, Ontario, Canada,
2
Department
of Medical Biophysics, University of Western Ontario,
London, Ontario, Canada,
3
Robarts
Research Institute, University of Western Ontario,
London, Ontario, Canada,
4
Department
of Biomedical Engineering, University of Western
Ontario, London, Ontario, Canada,
5
Department
of Obstetrics and Gynaecology, University of Western
Ontario, London, Ontario, Canada
Water-fat separation techniques using MRI have the
potential to provide fetal fat distributions in utero.
This metabolic information may have applications to
high-BMI expectant mothers and in detection of growth
restricted fetuses. Using the LAVA Flex sequence, we
obtained fetal fat fraction images in 7 patients,
including both normal weight and high-BMI patients. In
all cases, fat fraction maps could be segmented into
fetal subcutaneous and intra-abdominal compartments.
Fetal liver ROIs were obtained, demonstrating average
liver fat fractions of less than 1% in all fetuses. This
research demonstrates the technical viability of fetal
fat fraction in a clinical setting.
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