Abstract #0647
Age-Related Changes in Total Cerebral and Cardiac Blood Flow in Children and Adult Volunteers from 7 months to 60 years
Can Wu 1,2 , Samantha Schoeneman 3 , Amir Honarmand 2 , Susanne Schnell 2 , Michael Markl 1,2 , and Ali Shaibani 2,3
1
Biomedical Engineering, Northwestern
University, Chicago, Illinois, United States,
2
Radiology,
Northwestern University, Chicago, Illinois, United
States,
3
Medical Imaging, Ann & Robert H.
Lurie Children's Hospital of Chicago, Chicago, Illinois,
United States
The purpose of this study was to quantify both cerebral
arterial inflow using 4D flow and cardiac outflow with
2D phase-contrast MRI and investigate the age dependence
of changes in total cerebral arterial flow in relation
to aortic flow in a cohort of 40 normal subjects with
ages from 7 months to 60 years. The results demonstrated
age-related changes in both cerebral and aortic blood
flow as well as changes in their relationship,
indicating the importance of age-controlled control
groups for the detection of abnormal hemodynamics in
neurovascular diseases (e.g. cerebral arteriovenous
malformations, vein of Galen malformations, intracranial
atherosclerotic disease).
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