Abstract #0844
Automatic combined whole-body muscle and fat volume quantification using water-fat separated MRI in postmenopausal women
Janne West 1,2 , Thobias Romu 2,3 , Anna-Clara Spetz Holm 4 , Hanna Lindblom 1 , Lotta Lindh-strand 4 , Magnus Borga 2,3 , Mats Hammar 4 , and Olof Dahlqvist Leinhard 1,2
1
Department of Medical and Health Sciences,
Linkping University, Linkping, Sweden,
2
Center
for Medical Imaging Science and Visualization,
Linkping, Sweden,
3
Department
of Biomedical Engineering, Linkping University,
Linkping, Sweden,
4
Department
of Clinical and Experimental Medicine, Linkping
University, Linkping, Sweden
Quantitative and exact measurements of fat and muscle in
the body are important when addressing some of the
greatest health-challenges today. In this study
whole-body combined regional muscle and fat volume
quantification was validated in a group of
postmenopausal women, where the body composition is
changing. Twelve subjects were scanned with a 4-echo 3D
gradient-echo sequence. Water and fat image volumes were
calculated using IDEAL, and image intensity correction
was performed. Subsequently, automatic tissue
segmentation was established using non-rigid morphon
based registration. Whole-body regional fat and muscle
segmentation could be performed with excellent
test-retest reliability, in a single 7-minutes MR-scan.
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