Stimulated Echo Diffusion Weighted Imaging of the Liver at 3T
Hui Zhang 1 , Aiqi Sun 1 , Xiaodong Ma 1 , Zhe Zhang 1 , Ed X. Wu 2,3 , and Hua Guo 1
Center for Biomedical Imaging Research,
Department of Biomedical Engineering, School of
Medicine, Tsinghua University, Beijing, China,
of Biomedical Imaging and Signal Processing, The
University of Hong Kong, Hong Kong SAR, China,
of Electrical and Electronic Engineering, The University
of Hong Kong, Hong Kong SAR, China
Diffusion-weighted imaging (DWI) has been increasingly
used in clinical applications due to its sensitivity to
microscopic motion in biologic tissue. However, the DW
signal depends on not only b-value but also the
diffusion time due to restricted diffusion phenomenon.
This work proposed an optimized stimulated-echo (STE)
DWI method and aimed to investigate the dependence of
diffusion measurement on diffusion time in healthy human
liver. The results show that restricted diffusion
behavior is observed in human liver at 3T, which
demonstrates the effect of both b-value and diffusion
time on liver DWI quantification.
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