Skeletal Muscle Perfusion Measured with Pseudo-Continuous Arterial Spin-Labeling MRI After Dorsiflexion Contractions
Sean C Forbes 1 , Jingfeng Ma 1 , Glenn A. Walter 1 , Krista Vandenborne 1 , and Song Lai 1
University of Florida, Gainesville, Florida,
In this study we tested the feasibility of
pseudo-continuous arterial spin labeling (pCASL) MRI to
measure changes in skeletal muscle perfusion following a
short high-intensity dorsiflexion exercise protocol.
PCASL detected increases in perfusion of the primary
dorsiflexors (tibialis anterior and extensor digitorum
longus) after the contractions, and the perfusion values
were shown to have good day-to-day reproducibility. This
study shows the feasibility of applying pCASL to measure
skeletal muscle perfusion after isometric fatiguing
dorsiflexion contractions in healthy adults.
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