Myogenic Differentiation of Magnetically Labeled Mesenchymal Stem Cells
Natalie M. Pizzimenti 1 , Christiane Mallett 2 , Robert W. Wiseman 1,2 , and Erik M. Shapiro 2
Physiology Department, Michigan State
University, East Lansing, MI, United States,
Department, Michigan State University, East Lansing, MI,
The purpose of this study was to investigate the ability
of MSCs to differentiate into myogenic cells with
varying magnetic labeling conditions. MSCs show
morphological changes toward the myogenic lineage after
6 weeks in muscle media even with the introduction of
magnetic particles. This is a new tool that will allow
MRI-based cell tracking to further our understanding in
skeletal muscle repair.
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